Comprehensive safety studies spanning six months in rats (up to 100 mg/kg/day) and nine months in cynomolgus monkeys (up to 50 mg/kg/day) revealed no adverse findings, with NOAEL reaching the highest applied dosages
The best first step is to check with your insurance provider directly
Many protocols performed in hospitals in Brazil that receive patients affected by COVID-19 recommend supplementation or intramuscular injection of vitamin B 12 in cases where a deficiency or subclinical deficiency of vitamin B 12 is identified
Interventions affecting systemic metabolism, such as NNMT inhibition, are likely to influence the gut microbiome
Therefore, parenteral cyanocobalamin should be administered to a pregnant woman if the benefits outweigh the risks (10, 11)
Severe adverse events have not been a pattern in community usage, but human safety data is limited to a few pilot studies