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Mapping Microenvironment-Mediated Signaling Dependency of Targeted Inhibitors: A Mechanism-Based Approach of Selecting Effective Therapy Targeting Drug Resistant AML

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Interactions between Bax and Drp1 have also been implicated during mitochondrial fission in pathophysiological conditions, with spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis [75]

IV formulations can be effective, however the costs can be significant ($900 per session), factor in 4 sessions, for temporary results that typically last 3-8 weeks

doi: 10.1172/JCI93349DS1 [60] Heng MCY & Allen SG

10.1038/sj.cdd.4401373 Cell Death Differ