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doi: 10.1038/s41586-019-1484-9 304 ShengW

Vigorous shaking introduces air bubbles and can damage the peptide through mechanical agitation

However, redox homeostasis is conditioned by the magnitude and duration of exposure to free radicals, since constant exposure can have a serious impact on intracellular signals or genetic expression, resulting in irreversible pathological consequences (Rhee et al., 2003), since most reactions of the body are dependent on the redox state (Tan et al., 2018)

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There were no significant differences among groups in fasting glucose over the 12-week treatment period, using the repeated measures ANOVA