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The signs and symptoms of the deficiency may include anemia, the buildup of too much acid in the body (metabolic acidosis), frequent infections, and symptoms caused by problems in the brain including seizures, intellectual disability, and loss of coordination (ataxia)

The active site is located in a cleft situated between domains I and II and each subunit binds two molecules of a competitive inhibitor S-hexylglutathione

2a and Extended Data Fig

The approach involves pairing compounds that address tissue repair, hormonal support, and sleep quality

Strength improvements become measurable by 4-6 weeks

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