As a GLP-1 (glucagon-like peptide-1) receptor agonist, Ozempic stands out from other medications in its class due to several unique characteristics that directly benefit our patients
is supported, in part, by a Banting and Best Diabetes CentreNovo Nordisk Chair in Incretin Biology, a Sinai HealthNovo Nordisk Foundation Fund in Regulatory Peptides, CIHR grants 154321 and 19204 and Diabetes Canada-Canadian Cancer Society grant (OG-3- 24-5819-DD)
PureWay Blog
This approach could theoretically prevent Cas9 DNA integration into the host genome, thereby reducing the risk of unintended off-target effects and further enhancing the safety of LNP-based in vivo genome editing
Although no current evidence suggests that GLP-1RAs induce -catenin mutations or APC deficiencies, it is hypothesized that prolonged use of GLP-1RAs may foster the proliferative progression of colorectal cancer cells and pancreatic -cells, based on their mechanisms of action [99]
So excited to start this new health journey