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The most relevant differential diagnosis in this case would be to rule out the possibility of melanoma

It is one of the most studied and vital molecules in human biology

Prickaerts J, Moechars D, Cryns K, Lenaerts I, van Craenendonck H, Goris I, et al

12 The delayed gastric emptying induced by GLP-1 helps decrease postprandial hyperglycemia and induces a feeling of fullness, which is believed to contribute to a reduced appetite and, therefore, reduced food intake