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We found that PD-1 + non-exhausted-like T cells (PD-1 + Lag-3 ) displayed higher levels of GSH than exhausted-like (PD-1 + Lag-3 + ) and other control cell subsets (Supplemental Figure 1O), while stem-like progenitors (Ly108 + CD69 + ) displayed the highest levels of GSH among all cell subsets in transferred infiltrating CD8 + T cells (Supplemental Figure 1P)

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In cellular assays, exendin-4 exhibits similar potency as human GLP-1 in binding to and activating GLP-1R (86)

It is unclear at this stage whether the glass transition of the unfrozen part is involved with the cryoprotecting effect