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Understanding these elements helps patients approach their care with awareness and preparedness
Diabetes 64(3):715717 Aldawsari M, Almadani FA, Almuhammadi N, Algabsani S, Alamro Y, Aldhwayan M (2023) The efficacy of GLP-1 analogues on appetite parameters, gastric emptying, food preference and taste among adults with obesity: systematic review of randomized controlled trials
A 2025 systematic review and meta-analysis in Reviews in Endocrine and Metabolic Disorders found that tirzepatide (the active ingredient in Mounjaro and Zepbound) reduced hsCRP by approximately 33% and IL-6 by approximately 18% compared to placebo across patients with and without diabetes. A growing body of research suggests this effect occurs through direct action on the NF-B pathway, a master switch of inflammation
No new safety signals emerged, and the safety profile was consistent with the vast body of evidence for semaglutide
Siamashvili M, Davis SN (2021) Update on the effects of GLP-1 receptor agonists for the treatment of polycystic ovary syndrome
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