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Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high-fat diet-induced obesity in mice

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It can help lower cholesterol and glucose levels

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Combined with healthy habits, this supports long-term success and weight maintenance

"MOTS-c can significantly enhance physical performance in young, middle-age, and old mice." Reynolds et al., Nature Communications , 2021 [3] The ceiling on all of this is the same ceiling every mitochondrial peptide hits: the outcome data is rodent data