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2021 Sep 24;8:746247

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Semaglutide is a specific type of incretin-based medication known as a GLP-1 analogue

While weight loss medications have existed for decades, many of them are neither effective nor safe due to their amphetamine content or other potentially harmful ingredients

The complexity of pathology, cellular heterogeneity, and stage-dependent changes in disease progression make it difficult to disentangle ferroptosis-specific signals from overlapping oxidative stress responses

They result from slowed gastric emptying allowing bacterial fermentation in the stomach, and the change in gastric motility patterns during medication transitions can exacerbate them temporarily