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The firm has also been subject to regulatory issues and financial problems, but Catalent CEO Alessandro Maselli said the tide is now beginning to turn

However, the pipeline of oral and multi-agonist assets from Amgen, Viking Therapeutics, Structure Therapeutics, and others is expanding rapidly

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Historically, the obesity pharmacotherapy literature notes early trial signals and also that development was terminated after failure to show meaningful weight loss in a larger, longer trial (as summarized in a peer-reviewed review discussing a 12-week signal and a later 24-week negative result)