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Ishiguro K, Kitajima H, Niinuma T, Maruyama R, Nishiyama N, Ohtani H, et al

[DOI] [PubMed] [Google Scholar] 47.Urano T., Naganuma A., Imura N

27 In the early stage of T2D, impaired insulin synthesis and secretion plays a major role, with the stimuli reducing glucose-stimulated insulin secretion (GSIS), the basic function of cells

Give one properly formulated, FSSAI-compliant product a full month before deciding it "isn't working." This last point echoes what ICMR-NIN's own Dietary Guidelines for Indians (2024) emphasise more broadly: sustainable, consistent habits not one-off fixes are what actually move the needle on nutrition outcomes

349 If the ulcers fail to show a 50% reduction after 4 weeks of appropriate management via conventional methods, several advanced therapies, including negative-pressure therapy, growth factor therapy, bioengineered tissue, acellular matrix tissue, stem cell therapy, hyperbaric oxygen therapy, and, most recently, topical oxygen therapy, can be considered