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Rothe and J

3.2 Metformin and heart failure Heart failure (HF) is a clinical syndrome characterized by symptoms and/or signs resulting from structural or functional cardiac abnormalities, confirmed by elevated natriuretic peptide levels or objective evidence of pulmonary or systemic congestion ( 3.2.1 Preclinical evidence Experimental studies have shown that metformin exerts cardioprotective effects through multiple complementary mechanisms

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SCFA, short-chain fatty acid

Similar benefits were observed for other markers of the ageing process including lipid peroxides and protein oxidation due to the combination supplement

Heart, bone, and hydration strategies remain central to long-term health