Knowledge in this area is still sparse as structural modulation of the gut microbiome has only been reported at a relative low level of resolution (phylum/genus level) following treatment with agonists selective for the GLP-1 31,32,33,34 and GLP-2 25,35 receptors
There is limited data and no generally agreed upon consensus about exactly how and when a drug holiday should be initiated
Although reported data from trials and real-world series do not show definitive differences between GLP-1 RAs in terms of tolerability (Table 1), there are studies claiming that the tolerability profile may vary between different compounds [1,33,39]
Emesis after taking a long-acting GLP-1 receptor agonist for weight loss
Epel, E., Daubenmier, J., Moskowitz, J
The gross pathological description was of a lesion with dimensions 50 42 43 mm