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Standard injectable dosing ranges from 0.25 mg to 0.5 mg daily for most applications

10.1038/nrc.2016.71 Nat

In hypoxic conditions, HIF-1 acts as the main mediator of a series of in vivo pathophysiological responses, including angiogenesis, cell proliferation, and transcriptional induction of survival genes ( Erythropoietin (EPO) is the first protein that has been identified downstream of HIF-1 to activate erythropoiesis ( Shh signaling pathway The sonic hedgehog (Shh) signaling pathway plays an important role in endogenous neurogenesis (40)

Drug-Disease Interactions: No interactions found/established

PMC 8395423