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Dose levels for male mice were 0, 10, or 20 mg/kg body weight per day and for female mice 0, 20, or 40 mg/kg

Reduced insulin during a calorie deficit triggers natriuresis the kidneys retain less sodium, and water follows, increasing urine output

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Supplementing Glycine and N-Acetylcysteine (GlyNAC) in Older Adults Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Physical Function, and Aging Hallmarks: A Randomized Clinical Trial Liang, H., et al

It is especially important to drink plenty of liquids during and after physical activity

however, the role of sodium transported by the vitamin C cotransporter remains to be elucidated