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(More information) Several methodological issues (e.g., tests used to assess cognition, choice of study population, nature of the supplementation, study duration, etc.) may have contributed to the conflicting results observed in intervention studies

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Firstly, the FAERS database functions as a global spontaneous reporting system and inherently carries limitations such as uncertainty regarding the causality between the reported events and products, potential incomplete reporting, inaccuracies due to the publics level of awareness of a particular adverse reaction, and substantial missing information (e.g., medication dates, age, and weight, among others)