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Hospital systems were comparably affected, for example, UPMC out of Pittsburgh posted an even larger loss of about $370 million over the same term, which it attributed to increased medical utilization and pharmacy costs, while Highmark Health - also of Pittsburgh - despite avoiding operational losses, reported a significant decline in operating gains in 2024 relative to 2023, which administrators blame on high prescription drug costs - most notably GLP-1s

PlexusDx patients can discuss their specific alcohol use with their care team to personalize safety recommendations

Different GLP-1s should not be used at the same time

Wang et al., 2011)

Weight regains upon discontinuation of GLP-1RAs remain the major limitation