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Enteroviral 2B protein has been shown to interact with mitochondrial voltage-dependent anion channel 3 (VDAC3) to induce ROS production, and knockdown of VDAC3 significantly reduces EV71-induced mtROS generation and viral replication 132

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They should require comprehensive bloodwork and a thorough medical history before prescribing

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AOD-9604 works more slowly but targets the underlying tissue repair process

doi: 10.1016/j.bbrc.2020.11.037