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These receptors activate intracellular cascades mediated by gustducin, phospholipase C beta 2 (PLC2), inositol triphosphate (IP3), and Transient Receptor Potential Melastatin 5 (TRPM5), leading to the release of ATP as a neurotransmitter (47)

Digestive Troubles: A lack of B12 can lead to digestive issues, impairing your body's ability to absorb essential nutrients and causing discomfort

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2015;33(1 Suppl 88):S82-5

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For homeostatic feeding assessment using SD, mice were fasted overnight, whereas for hedonic feeding assessment (HFD), mice had ad libitum access to standard chow before testing