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When melanin is overproduced or unevenly distributed, visible darkened areas can develop, presenting as hyperpigmentation or patchy tone

How Bioavailability Bioavailability refers to the percentage of a substance that reaches systemic circulation in an active form after administration

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The RAS also promotes inflammation, oxidative stress, and tissue remodeling [57,58]), processes involved in what is now called the neuronal inflammatory response which is a key factor in neurodegenerative disease [59,60]