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In crude analyses, GLP-1 receptor agonist use was associated with an increased incidence of suicidality compared with DPP-4 inhibitors (crude incidence rates 3.9 v 1.8 per 1000 person years, respectively

After matching, there were no significant differences in the baseline characteristics between groups (absolute SD values 50%, and the composite renal outcomes

Current evidence does not support a direct causal relationship between Ozempic and anger issues, but individual experiences may vary, and further research into the psychological effects of GLP-1 agonists would be valuable

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2.9 Histological and immunofluorescence examination The animals were sacrificed, and the organs were isolated and transferred to Eppendorf tubes prefilled with 4% paraformaldehyde