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Key findings across trials were narratively synthesized to identify trends in sustained weight loss, cardiometabolic effects, adverse events, and treatment discontinuation

KPV also reduces NF-kappaB and mitogen-activated protein kinase activity

[7] [8] GLP-1 receptor agonists (such as semaglutide, liraglutide, and dulaglutide) are now widely prescribed medications for type 2 diabetes and obesity management, approved by the MHRA and recommended in NICE guidelines (NG28 for type 2 diabetes

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