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Tirzepatide is a once-weekly injectable that activates two appetite-regulating gut hormones GIP and GLP-1 to curb hunger, slow digestion, and steady blood sugar
Additionally, TCIs are less potent than high-potency TCS, making them less effective for severe or hyperkeratotic CHE and are predominantly indicated for AD, and not CHE [71, 88, 90]
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While drugs used to treat diabetes inhibit this enzyme to prolong GLP-1 action on blood glucose, they do not translate to a significant effect on food intake
This modest improvement aligns with the weight loss benefit itself: losing 1015% of body weight typically lowers blood pressure independent of medication effects
Because these medications are so powerful, a licensed provider will determine which single medication is right for you, rather than prescribing both
