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Herein, we found that children born to parents with obesity had increased fasting insulin levels and HOMA-IR scores, in agreement with previous clinical [32, 33] and experimental [10] studies describing that PO may disrupt cell development in the offspring, thus impairing insulin production and function

[3] The reduction in number of injections required may decrease the risk of non-adherence due to forgetfulness or unwillingness to self-inject medication

in multiple mouse models of obesity, this led to a decrease in body weight and the correction of dyslipidemia [141]

(2021) 160:145157.e148

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