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Possible side effects of GLP-1s (Wegovy, Saxenda, Zepbound) Side effects tend to be focused on the gastrointestinal system, where these medications work by changing gut hormones

Further analyses of differentially expressed genes between GLP-1MK-801 and semaglutide treatment groups support this notion by showing enrichment of functional terms pertaining to glutamatergic signalling and synaptic plasticity among the most upregulated genes

A major side effect of this class of drugs is rapid weight loss

The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses

These findings underscore that GLP-1 therapy is a long-term intervention rather than a short-term solution

The samples were processed by pretreatment with 6 M urea for 30 min at 0 C followed by 20% trichloroacetic acid in acetone (wt./v%) at 20 C overnight