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11 didnt require insulin for between one and five years and 10 were insulin-free for more than five years

Body composition shifts are real but modest, typically a few pounds of visceral fat reduction and improved muscle definition over months, not the dramatic scale changes seen with semaglutide or tirzepatide

However, postprandial TG excursion and plasma levels of active GLP-1 were not different between Dpp4 EC/ (BMT) and Dpp4 EC+/+ (BMT) mice (Figure 2F)