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Neurol Neuroimmunol Neuroinflamm (2022) 9(2):e1138

Quantitative PCR was performed to assess the mRNA expression levels of TNF-, IL-6, and IL-1, with GAPDH used as a loading control

315 Subsequently, rats were treated with liraglutide through subcutaneous injection to observe its therapeutic effect on OA

Additionally, while clinical guidelines for indicated use of GLP-1 RAs are rapidly changing as evidence for GLP-1 RA use evolves, the ethics of off-label use are particularly important to consider given the impact these shortages can have on access for patients who otherwise have a strong clinical indication to be on them

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