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It inhibited serotonin- and epinephrine-induced platelet aggregation in vitro and ex vivo [125,126]

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In some cases, most of the tumor cells were large melanin-producing epithelioid cells ( Figures 2DF ), while other cases were predominant with small neuroblast-like cells ( Figures 2GI )

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Therefore, high localized concentrations of metformin may have contributed to the consequence of side effects such as gastrointestinal distress