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They interact closely with nerve cells within the enteric nervous system (ENS), the second brain that governs gut motility, emotion, and inflammation

Anti-inflammatory and glial effects In preclinical models, GLP-1R activation suppresses microglial activation and lowers central production of TNF-alpha, IL-1 beta, and IL-6

A combination therapy for androgenic alopecia based on quercetin and zinc/copper dual-doped mesoporous silica nanocomposite microneedle patch

In contrast, retatrutide, currently undergoing clinical studies, shows promise for enhanced effectiveness, potentially offering up to a 24.2% reduction in mass over 48 weeks

And that means it's only a matter of time before the bacteria or archaea come back

Caturano et al., 2023)