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Further experiments found that low-dose berberine can promote cell survival and antioxidant effects by up-regulating PI3K/AKT/Bcl-2 and Nrf2/HO-1 signal pathways

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Endogenous substances found within cells can be categorized into enzymatic antioxidants, which include superoxide dismutase (SOD), catalases (CAT), and peroxidases, or non-enzymatic antioxidants, which encompass tocopherol, glutathione, and ascorbic acid (78)

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