Strategic meal planning can help minimise these effects whilst maintaining nutritional adequacy
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Key trials like STEP, SURPASS, and SELECT have demonstrated their efficacy in glycemic control (HbA1c reductions of 1.02.0%) [1, 3, 4], weight loss (1020% mean body weight reduction) [2, 3, 4], and cardiovascular risk reduction [4, 7]
Significantly downregulated proteins when adjusting for body weight effects in STEP 1 known to be associated with CVD risk included tenascin C (TNC), NT-proBNP, thrombospondin 2 (THBS2), complement component C1q receptor (cluster of differentiation 93 (CD93)), macrophage scavenger receptor 1extracellular domain (MSR1) and angiopoietin-2 (ANGPT2)
Wait at least 30 minutes before eating, drinking anything else, or taking other pills
DBL, Eumseong, Korea) were fasted overnight before drug administration