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Endocrinology (1995) 136(8):358596

They include an N-terminal 120160 residue extracellular domain (ECD) and a C-terminal transmembrane domain (TMD), both of which are important for peptide hormone binding and activation 2

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Where VEGFR2- blocking, human anti-VEGF immunoconjugates are used, it will also be understood that coagulant immunoconjugates can generally be used at higher doses than toxin immunoconjugates