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In this condition of viral infection, oxidative stress is imposed by GSH depletion, occurring in two steps and following direct virus challenge of the cell membrane, without the intervention of ROS (Ciriolo et al., 1997)

Infection, some medications and foods with high level of convicine, vicine, divicine and isouramil such as fava beans can cause oxidative stress

Elevated levels of oxidative stress as a result of G6PD deficiency cultivate a favorable environment for viral replication, consequently deteriorating the course of infection [12]