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(PubMed) Herrick KA, Perrine CG, Aoki Y, Caldwell KL

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These neural changes correlated with reduced caloric intake, suggesting that the hormone modulates central appetite regulation independently of gastrointestinal effects

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Calcium entry through the compromised plasma membrane has been shown to activate proteases (calpain, calcineurin), resulting in neurofilament degradation, disruption of axonal transport, and functional failure (Schlaepfer, 1974, 1987)

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