Overall, this is a well tolerated ingredient with no significant safety concerns flagged
One sachet contains 5000 mg of creatine Creavitalis
doi: 10.2967/jnumed.109.066647 201 van BerckelBNBossongMGBoellaardRKloetRSchuitemakerACaspersEet al
Stay hydrated: Drinking plenty of water helps digestion and prevents constipation
With respect to transporters, SLCO1B1, SLCO2B1, and ABCG2 are good candidates, whereas proper functional characterization of ABCB1 is necessary prior to applying any strong conclusions of their association with SIM
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