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Development and comparative in vitro and in vivo study of BNN27 mucoadhesive liposomes and nanoemulsions for nose-to-brain delivery
DCI is synthesized by an insulin-dependent epimerase that converts MI into DCI
These effects are frequently dose-dependent
And people went along with it
Furthermore HLA-DR expression is reduced in the peripheral blood DCs of elderly subjects, which leads to diminished antigen presentation and contributes to the age-related decline in immune responsiveness [256]
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