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Plasma half-life studies in research models consistently show 4560 minute elimination half-lives, translating to 45 half-lives (roughly 45 hours) for 94% clearance and 67 half-lives (68 hours) for 99% clearance

Observations in large animal models such as cattle and swine have suggested that IGF-1 LR3 exposure may be associated with sustained cellular turnover

Maebashi M, Kawamura N, Sato M, Imamura A, Yoshinaga K

doi:10.1016/j.jaip.2019.05.034 7Hemstreet BA, Page RL 2nd