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Central to the pathophysiology of HFpEF is diastolic impairment, mediated by increased ventricular stiffness due to maladaptive responses to biomechanical stress, including pressure overload, aberrant myocardial strain patterns, and pathological extracellular matrix (ECM) remodeling[5]

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The added bonus of continuous support through online check-ins and dosage adjustments makes it easier to stay on track, and the fact that they help with side effects (like nausea) really shows they care about your experience