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Estrogen can also impact mitochondrial biogenesis, function, and regulation of ATP production.[ref] In a nutshell, estrogen causes the body to increase the production of other hormones, growth factors, and metabolic factors

Can Glutathione Really Whiten Your Skin

Nat Genet 2002;32:261-6

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Beyond being a metabolic byproduct, lactate serves as an immunometabolite that shapes inflammatory responses, intracellular lactate accumulation promotes protein lactylation and modulation of downstream gene expression and immune function