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As of 2026, retatrutide is still in Phase 3 clinical trials (the TRIUMPH program) and has not yet received FDA approval

As with all GLP-1 based medications, the most common side effects include nausea, vomiting, diarrhoea, and constipation particularly during dose titration

Levels of IGF-1 remained unchanged with this once-daily regimen [12]

Fortunately, the side effects with semaglutide and tirzepatide usually improve after your body adjusts to the medication

On Day 0 and Day 11 of the treatment with 3 g kg 1 d-allulose, glucose levels in the tail vein blood were measured with GlucoCard DIA meter in mice fasted 4 h (9:0013:00)