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However, some people may experience redness, itching, or irritation

doi: 10.3389/fphys.2023.1133528 46

Upregulated genes were enriched in pathways related to the DNA damage response and glutathione metabolism, implying oxidative stress-induced DNA damage

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The pharmaceutical industry has leveraged the capacity of medium-chain fatty acids and their derivatives to transiently and reversibly open epithelial TJs in formulations to enable oral administration of therapeutic peptides, some of which have received regulatory approval or are progressing in advanced clinical trials

*Correspondence: Bengt Mannervik, [email protected] This article was submitted to Cellular Biochemistry, a section of the journal Frontiers in Molecular Biosciences Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers