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Abbreviations GLP-1: glucagon-like peptide 1 GIP: glucose-dependent insulinotropic polypeptide [Ca 2+ ] i : intracellular Ca 2+ concentrations Adcy: adenylate cyclase CICR: Ca 2+ -induced Ca 2+ release T2D: type 2 diabetes mellitus NOTES

Gallbladder problems: Rapid weight loss from any cause can increase gallstone risk

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Diabetes Management : Medications like Ozempic use semaglutide to help control blood sugar levels in individuals with type 2 diabetes