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While some studies in PD models have revealed neuroprotective functions related to dopaminergic neuron survival, others have suggested a proinflammatory effect in LPS-treated models in which IL-4 exacerbates microglial activation and BBB disruption [187, 211]

p-Coumaric acid protects against D-galactose induced neurotoxicity by attenuating neuroinflammation and apoptosis in mice brain

Pharmacologically, FOXO4-DRI exhibits: Senolytic Activity: Targets and induces apoptosis in senescent cells, reducing systemic inflammation and restoring tissue homeostasis (3, 9)

BPC-157 (Body Protection Compound): The Tissue Repair Peptide BPC-157 is a synthetic peptide derived from a protective protein found in human gastric juice