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Oral protein delivery: Current status and future prospect

Isaacs stresses

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The concentration of L-glutamate was then calculated using a standard calibration curve, normalized to protein sample concentrations, and levels expressed as percentage relative to controls

Notably, a combined analysis of TSPO-PET and FDG-PET imaging indicates that neuroinflammation and metabolic dysfunction may coexist within the central nervous system, yet remain relatively independent

Otherwise if such studies consistently provide negative results then a falsification threshold of MAD could be argued, similar to the Tau and amyloid casual theories (Espay et al., 2023)