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Metabolic dysfunction-associated steatotic liver disease (MASLD) MASLD is the most prevalent CLD globally, with a global prevalence of approximately 32% (estimated in 2022) and is strongly associated with obesity, dyslipidemia, and insulin resistance 46,47

J., Augustsson, K., Fraser, G

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People report decreased appetite as early as one week, and significantly less hunger, reduced eating, and fewer cravings starting between weeks 3 and 8