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Quick Answer: Potentially yes they work through different pathways and may be complementary but this combination requires careful medical supervision and has not been studied in clinical trials

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Clinical Benefits IGF-1 LR3 drives rapid muscle protein synthesis and hypertrophy while MOTS-C ensures adequate cellular energy to support sustained anabolic activity and training intensity

Similarly, Hu et al

The advantage of this approach is that it combines two minimally invasive and reversible weight loss strategies, which in the future may provide patients with an alternative approach to weight loss

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