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Studies show that weight regain begins within days of stopping GLP-1 therapy, with patients returning to baseline eating patterns and losing 50% or more of their weight loss gains within a year

Moreover, SZD treatment reduced the expression level of HIF-1 and its subsequent transcriptional target VEGF, which in turn reduced the angiogenesis and decreased the volume of endometriotic lesions

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Eur J Pharm Sci 25(1):5765

Drug Metab Rev 1998, 30 (2), 245275