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Vilsboll T, Holst JJ

Researchers estimate that more than 1 billion people globally live with migraine, a neurological condition causing severe, chronic headaches that are often accompanied by other issues such as nausea and light sensitivity

It does not invalidate the research, but it does mean human extrapolation should be conservative

The mechanism is not entirely clear, but B12 plays a role in nervous system function and neurotransmitter synthesis, which may help modulate the nausea response triggered by GLP-1 receptor activation in the brainstem

Individual medication resistance

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