However, emerging KD modifications, such as the MAD or MCT-KD, have shown improved tolerability in some studies [199, 200], suggesting their potential for better long-term adherence
Concurrently, probiotic treatment induced a marked downregulation of the pro-inflammatory mediators interferon- (IFN-) and tumor necrosis factor- (TNF-) (248)
This imbalance, characterized by increased GABA synthesis and impaired degradation, suggests a mechanistic explanation for the excessive astrocytic GABA observed in PTSD
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As an outcome, colonocytes shift to anaerobic metabolism characterised by reduced oxygen consumption thereby facilitating the growth of facultative anaerobes such as Enterobactericeae, which exploit the loss of epithelial hypoxia through aerobic respiration (Byndloss et al
doi: 10.1016/j.cmi.2018.08.002 108 ElkinsM.JainN.Tkel